Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2

por Ricardo A. P. Pádua, Yizhi Sun, Ingrid Marko, Warintra Pitsawong, John B. Stiller, Renee Otten, Dorothee Kern
Publicado 2018

Rescue of conformational dynamics in enzyme catalysis by directed evolution

por Renee Otten, Lin Liu, Lillian R. Kenner, Michael W. Clarkson, David Mavor, Dan S. Tawfik, Dorothee Kern, James S. Fraser
Publicado 2018