A molecular switch regulating transcriptional repression and activation of PPARγ

por Jinsai Shang, Sarah A. Mosure, Jie Zheng, Richard Brust, Jared Bass, Ashley Nichols, Laura A. Solt, Patrick R. Griffin, Douglas J. Kojetin
Publicado 2020

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

por William H. Hudson, Ian Mitchelle S. de Vera, Jerome C. Nwachukwu, Emily R. Weikum, Austin G. Herbst, Qin Yang, David L. Bain, Kendall W. Nettles, Douglas J. Kojetin, Eric A. Ortlund
Publicado 2018

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

por Richard Brust, Jinsai Shang, Jakob Fuhrmann, Sarah A. Mosure, Jared Bass, Andrew Cano, Zahra Heidari, Ian M. Chrisman, Michelle D. Nemetchek, Anne-Laure Blayo, Patrick R. Griffin, Theodore M. Kamenecka, Travis S. Hughes, Douglas J. Kojetin
Publicado 2018

Defining a conformational ensemble that directs activation of PPARγ

por Ian M. Chrisman, Michelle D. Nemetchek, Ian Mitchelle S. de Vera, Jinsai Shang, Zahra Heidari, Yanan Long, Hermes Reyes-Caballero, Rodrigo Galindo-Murillo, Thomas E. Cheatham, Anne-Laure Blayo, Youseung Shin, Jakob Fuhrmann, Patrick R. Griffin, Theodore M. Kamenecka, Douglas J. Kojetin, Travis S. Hughes
Publicado 2018