Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

par Neophytos Christodoulou, Antonia Weberling, Douglas Strathdee, Kurt I. Anderson, Paul Timpson, Magdalena Zernicka-Goetz
Publié 2019

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap

par Anna Woroniuk, Andrew Porter, Gavin White, Daniel T. Newman, Zoi Diamantopoulou, Thomas Waring, Claire Rooney, Douglas Strathdee, Daniel J. Marston, Klaus M. Hahn, Owen J. Sansom, Tobias Zech, Angeliki Malliri
Publié 2018

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

par Andreas K. Hock, Eric C. Cheung, Timothy J. Humpton, Tiziana Monteverde, Viola Paulus-Hock, Pearl Lee, Ewan McGhee, Alessandro Scopelliti, Daniel J. Murphy, Douglas Strathdee, Karen Blyth, Karen H. Vousden
Publié 2017

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

par Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant
Publié 2021

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

par Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom
Publié 2021