MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

by En-Chi Hsu, Michelle Shen, Merve Aslan, Shiqin Liu, Manoj Kumar, Fernando Garcia-Marques, Holly M. Nguyen, Rosalie Nolley, Sharon J. Pitteri, Eva Corey, James D. Brooks, Tanya Stoyanova
Published 2021

Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer

by Yiting Lim, Sonali Arora, Samantha L. Schuster, Lukas Corey, Matthew Fitzgibbon, Cynthia L. Wladyka, Xiaoying Wu, Ilsa M. Coleman, Jeffrey J. Delrow, Eva Corey, Lawrence D. True, Peter S. Nelson, Gavin Ha, Andrew C. Hsieh
Published 2021

A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture

by Elise Y. Cai, Jose Garcia, Yuzhen Liu, Funda Vakar-Lopez, Sonali Arora, Holly M. Nguyen, Bryce Lakely, Lisha Brown, Alicia Wong, Bruce Montgomery, John K. Lee, Eva Corey, Jonathan L. Wright, Andrew C. Hsieh, Hung-Ming Lam
Published 2021

Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression

by Marco Bolis, Daniela Bossi, Arianna Vallerga, Valentina Ceserani, Manuela Cavalli, Daniela Impellizzieri, Laura Di Rito, Eugenio Zoni, Simone Mosole, Angela Rita Elia, Andrea Rinaldi, Ricardo Pereira Mestre, Eugenia D’Antonio, Matteo Ferrari, Flavio Stoffel, Fernando Jermini, Silke Gillessen, Lukas Bubendorf, Peter Schraml, Arianna Calcinotto, Eva Corey, Holger Moch, Martin Spahn, George Thalmann, Marianna Kruithof-de Julio, Mark A. Rubin, Jean-Philippe P. Theurillat
Published 2021

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

by Paloma Cejas, Yingtian Xie, Alba Font-Tello, Klothilda Lim, Sudeepa Syamala, Xintao Qiu, Alok K. Tewari, Neel Shah, Holly M. Nguyen, Radhika A. Patel, Lisha Brown, Ilsa Coleman, Wenzel M. Hackeng, Lodewijk Brosens, Koen M. A. Dreijerink, Leigh Ellis, Sarah Abou Alaiwi, Ji-Heui Seo, Sylvan Baca, Himisha Beltran, Francesca Khani, Mark Pomerantz, Alessandra Dall’Agnese, Jett Crowdis, Eliezer M. Van Allen, Joaquim Bellmunt, Colm Morrisey, Peter S. Nelson, James DeCaprio, Anna Farago, Nicholas Dyson, Benjamin Drapkin, X. Shirley Liu, Matthew Freedman, Michael C. Haffner, Eva Corey, Myles Brown, Henry W. Long
Published 2021

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

by Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, Justin Hwang, Sheng Yu Ku, Rand Arafeh, Taylor Arnoff, Supreet Agarwal, Connor Bell, Edward O’Connor, Xintao Qiu, Sarah Abou Alaiwi, Rosario I. Corona, Marcos A. S. Fonseca, Claudia Giambartolomei, Paloma Cejas, Klothilda Lim, Monica He, Anjali Sheahan, Amin Nassar, Jacob E. Berchuck, Lisha Brown, Holly M. Nguyen, Ilsa M. Coleman, Arja Kaipainen, Navonil De Sarkar, Peter S. Nelson, Colm Morrissey, Keegan Korthauer, Mark M. Pomerantz, Leigh Ellis, Bogdan Pasaniuc, Kate Lawrenson, Kathleen Kelly, Amina Zoubeidi, William C. Hahn, Himisha Beltran, Henry W. Long, Myles Brown, Eva Corey, Matthew L. Freedman
Published 2021