MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies

por Andrew D. White, Laura Sibley, Charlotte Sarfas, Alexandra Morrison, Jennie Gullick, Simon Clark, Fergus Gleeson, Anthony McIntyre, Cecilia Lindestam Arlehamn, Alessandro Sette, Francisco J. Salguero, Emma Rayner, Esteban Rodriguez, Eugenia Puentes, Dominick Laddy, Ann Williams, Mike Dennis, Carlos Martin, Sally Sharpe
Publicado 2021

High-dose Mycobacterium tuberculosis aerosol challenge cannot overcome BCG-induced protection in Chinese origin cynomolgus macaques; implications of natural resistance for vaccine...

por Laura Sibley, Andrew D. White, Karen E. Gooch, Lisa M. Stevens, Rachel Tanner, Ashley Jacobs, Owen Daykin-Pont, Fergus Gleeson, Anthony McIntyre, Randall Basaraba, Simon Clark, Graham Hall, Geoff Pearson, Emma Rayner, Helen McShane, Ann Williams, Mike Dennis, Philip D. Marsh, Sally Sharpe
Publicado 2021

Towards nationally curated data archives for clinical radiology image analysis at scale: Learnings from national data collection in response to a pandemic

por Dominic Cushnan, Rosalind Berka, Ottavia Bertolli, Peter Williams, Daniel Schofield, Indra Joshi, Alberto Favaro, Mark Halling-Brown, Gergely Imreh, Emily Jefferson, Neil J Sebire, Gerry Reilly, Jonathan C L Rodrigues, Graham Robinson, Susan Copley, Rizwan Malik, Claire Bloomfield, Fergus Gleeson, Moira Crotty, Erika Denton, Jeanette Dickson, Gary Leeming, Hayley E Hardwick, Kenneth Baillie, Peter JM Openshaw, Malcolm G Semple, Caroline Rubin, Andy Howlett, Andrea G Rockall, Ayub Bhayat, Daniel Fascia, Cathie Sudlow, Joseph Jacob
Publicado 2021