Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.

por Hlumani Ndlovu, Mathew Darby, Monika Froelich, William Horsnell, Fred Lühder, Thomas Hünig, Frank Brombacher
Publicado 2014

BALB/c mice deficient in CD4 T cell IL-4Rα expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

por Karen J Bryson, Owain R Millington, Thabang Mokgethi, H Adrienne McGachy, Frank Brombacher, James Alexander
Publicado 2011

Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs

por Sonika Patial, Brandon W. Lewis, Thao Vo, Ishita Choudhary, Kshitiz Paudel, Yun Mao, Dhruthi Singamsetty, Frank Brombacher, Yogesh Saini
Publicado 2021

Nippostrongylus-induced intestinal hypercontractility requires IL-4 receptor alpha-responsiveness by T cells in mice.

por Saskia Schmidt, J Claire Hoving, William G C Horsnell, Helen Mearns, Antony J Cutler, Tiroyaone M Brombacher, Frank Brombacher
Publicado 2012

Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.

por Peter C Cook, Sarah A Aynsley, Joseph D Turner, Gavin R Jenkins, Nico Van Rooijen, Mosiuoa Leeto, Frank Brombacher, Adrian P Mountford
Publicado 2011

IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection.

por William G C Horsnell, Matthew G Darby, Jennifer C Hoving, Natalie Nieuwenhuizen, Henry J McSorley, Hlumani Ndlovu, Saeeda Bobat, Matti Kimberg, Frank Kirstein, Anthony J Cutler, Benjamin Dewals, Adam F Cunningham, Frank Brombacher
Publicado 2013

Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection

por Marion Rolot, Annette M. Dougall, Alisha Chetty, Justine Javaux, Ting Chen, Xue Xiao, Bénédicte Machiels, Murray E. Selkirk, Rick M. Maizels, Cornelis Hokke, Olivier Denis, Frank Brombacher, Alain Vanderplasschen, Laurent Gillet, William G. C. Horsnell, Benjamin G. Dewals
Publicado 2018

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

por Sugata Roy, Sebastian Schmeier, Bogumil Kaczkowski, Erik Arner, Tanvir Alam, Mumin Ozturk, Ousman Tamgue, Suraj P. Parihar, Hideya Kawaji, Masayoshi Itoh, Timo Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Reto Guler, Vladimir B. Bajic, Frank Brombacher, Harukazu Suzuki
Publicado 2018