An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase

por Veronika Csizmok, Stephen Orlicky, Jing Cheng, Jianhui Song, Alaji Bah, Neda Delgoshaie, Hong Lin, Tanja Mittag, Frank Sicheri, Hue Sun Chan, Mike Tyers, Julie D. Forman-Kay
Publicado 2017

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1

por Salima Daou, Haithem Barbour, Oumaima Ahmed, Louis Masclef, Caroline Baril, Nadine Sen Nkwe, Daméhan Tchelougou, Maxime Uriarte, Eric Bonneil, Derek Ceccarelli, Nazar Mashtalir, Mika Tanji, Jean-Yves Masson, Pierre Thibault, Frank Sicheri, Haining Yang, Michele Carbone, Marc Therrien, El Bachir Affar
Publicado 2018

A substrate binding model for the KEOPS tRNA modifying complex

por Jonah Beenstock, Samara Mishelle Ona, Jennifer Porat, Stephen Orlicky, Leo C. K. Wan, Derek F. Ceccarelli, Pierre Maisonneuve, Rachel K. Szilard, Zhe Yin, Dheva Setiaputra, Daniel Y. L. Mao, Morgan Khan, Shaunak Raval, David C. Schriemer, Mark A. Bayfield, Daniel Durocher, Frank Sicheri
Publicado 2020

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

por Mandeep K. Gill, Tania Christova, Ying Y. Zhang, Alex Gregorieff, Liang Zhang, Masahiro Narimatsu, Siyuan Song, Shawn Xiong, Amber L. Couzens, Jiefei Tong, Jonathan R. Krieger, Michael F. Moran, Alexandre R. Zlotta, Theodorus H. van der Kwast, Anne-Claude Gingras, Frank Sicheri, Jeffrey L. Wrana, Liliana Attisano
Publicado 2018