Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation

por Julia O’Sullivan, Maria Tedim Ferreira, Jean-Philippe Gagné, Ajit K. Sharma, Michael J. Hendzel, Jean-Yves Masson, Guy G. Poirier
Publicado 2019

Molecular mechanism of the MORC4 ATPase activation

por Adam H. Tencer, Khan L. Cox, Gregory M. Wright, Yi Zhang, Christopher J. Petell, Brianna J. Klein, Brian D. Strahl, Joshua C. Black, Michael G. Poirier, Tatiana G. Kutateladze
Publicado 2020

Accessibility of the histone H3 tail in the nucleosome for binding of paired readers

por Jovylyn Gatchalian, Xiaodong Wang, Jinzen Ikebe, Khan L. Cox, Adam H. Tencer, Yi Zhang, Nathaniel L. Burge, Luo Di, Matthew D. Gibson, Catherine A. Musselman, Michael G. Poirier, Hidetoshi Kono, Jeffrey J. Hayes, Tatiana G. Kutateladze
Publicado 2017

The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations

por Brianna J. Klein, Anagha Deshpande, Khan L. Cox, Fan Xuan, Mohamad Zandian, Karina Barbosa, Sujita Khanal, Qiong Tong, Yi Zhang, Pan Zhang, Amit Sinha, Stefan K. Bohlander, Xiaobing Shi, Hong Wen, Michael G. Poirier, Aniruddha J. Deshpande, Tatiana G. Kutateladze
Publicado 2021

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks

por Marie-Christine Caron, Ajit K. Sharma, Julia O’Sullivan, Logan R. Myler, Maria Tedim Ferreira, Amélie Rodrigue, Yan Coulombe, Chantal Ethier, Jean-Philippe Gagné, Marie-France Langelier, John M. Pascal, Ilya J. Finkelstein, Michael J. Hendzel, Guy G. Poirier, Jean-Yves Masson
Publicado 2019

Assessing the Course of Organ Dysfunction Using Joint Longitudinal and Time-to-Event Modeling in the Vasopressin and Septic Shock Trial

por Michael O. Harhay, PhD, Alessandro Gasparini, PhD, Allan J. Walkey, MD, MS, Gary E. Weissman, MD, MSHP, Michael J. Crowther, PhD, Sarah J. Ratcliffe, PhD, James A. Russell, MD, on behalf of the Vasopressin and Septic Shock Trial (VASST) Investigators, J. A. Russell, K. R. Walley, C. L. Holmes Boulton, J. T. Granton, P. C. Hebert, D. J. Cooper, S. Mehta, J. Singer, A. C. Gordon, M. M. Storms, S. Jones, J. A. Russell, M. M. Storms, K. R. Walley, G. R. Bernard, A. S. Slutsky, G. A. Wells, A. Gasparini, B. Savage, D. Ayers, R. Woods, K. Wu, M. Maralit, L. Smith, K. Foley, A. Suri, M. Steinberg, B. Howe, P. Galt, A. Higgins, M. M. Storms, M. E. LeBlanc, A. M. Sutherland, A. Sham, A. McLeod, D. R. Dorscheid, M. Hameed, L. Lazosky, S. Helderweirt, C. Honeyman, T. Terins, D. Chittock, J. Ronco, L. Smith, S. Logie, G. Wood, F. Auld, V. Stedham, M. Mantle, L. Fox, G. D. McCauley, J. D. Rolf, C. Erbacher, G. Martinka, S. Goulding, S. Silverwood, L. Leung, S. Keenan, J. Murray, M. Van Osch, B. Light, M. Dominique, P. Gray, R. Stimpson, S. Rosser, D. Bell, W. Janz, P. C. Hebert, T. McArdle, I. Watpool, J. T. Granton, M. Steinberg, A. Matte-Martyn, D. J Cook, E. McDonald, F. Clarke, A. Tkaczyk, N. Zytaruk, T. Stewart, A. Suri, C. Martinez-Motta, R. MacDonald, V. Sivanantham, R. Hodder, J. Foxall, M. Lewis, M. Ward, C. Dos Santos, J. Friedrich, D. Scales, O. Smith, I. DeCampos, A. Richards, H. Michalopoulos, U. Bakshi, W. Sibbald, T. Smith, K. Code, B. Bojilov, C. Dale, M. Keogh, M. Meade, L. Hand, C. Martin, J. Kehoe, V. Binns, M. McGuire, G. Poirier, L. Provost, J. Muscedere, C. Diemer, D. J. Cooper, V. Pellegrino, A. Hilton, S. Morrison, C. Weatherburn, K. Moulden, C. Harry, J. J. Presneill, M. S Robertson, J. F. Cade, B. D. Howe, D. K. Barge, C. A. Boyce, F. Healy, C. Wright, D. Weyandt, J. Barrett, C. Walker, P. Galt, S. Burton, G. Dobb, S. Perryman, J. Chamberlain, L. Thomas, A. Bersten, L. Daly, T. Hunt, D. Wood, B. Patel, J. Larson, M. Rady, G. LeBrun, E. Boyd, R. Rush
Publicado 2020