Regulatory mechanisms of incomplete huntingtin mRNA splicing

par Andreas Neueder, Anaelle A. Dumas, Agnesska C. Benjamin, Gillian P. Bates
Publié 2018

Genetic knock-down of HDAC3 does not modify disease-related phenotypes in a mouse model of Huntington's disease.

par Lara Moumné, Ken Campbell, David Howland, Yingbin Ouyang, Gillian P Bates
Publié 2012

Ablation of kynurenine 3-monooxygenase rescues plasma inflammatory cytokine levels in the R6/2 mouse model of Huntington’s disease

par Marie Katrin Bondulich, Yilan Fan, Yeojin Song, Flaviano Giorgini, Gillian P. Bates
Publié 2021

The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction

par Casandra Gomez-Paredes, Michael A. Mason, Bridget A. Taxy, Aikaterini S. Papadopoulou, Paolo Paganetti, Gillian P. Bates
Publié 2021

Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in Huntington’s disease models

par Michael A. Mason, Casandra Gomez-Paredes, Kirupa Sathasivam, Andreas Neueder, Aikaterini-Smaragdi Papadopoulou, Gillian P. Bates
Publié 2020

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington’s disease patients

par Andreas Neueder, Christian Landles, Rhia Ghosh, David Howland, Richard H. Myers, Richard L. M. Faull, Sarah J. Tabrizi, Gillian P. Bates
Publié 2017

Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice.

par Silvia Corrochano, Maurizio Renna, Georgina Osborne, Sarah Carter, Michelle Stewart, Joel May, Gillian P Bates, Steve D M Brown, David C Rubinsztein, Abraham Acevedo-Arozena
Publié 2014