Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy

por Jennifer E. Adair, Timothy Waters, Kevin G. Haworth, Sara P. Kubek, Grant D. Trobridge, Jonah D. Hocum, Shelly Heimfeld, Hans-Peter Kiem
Publicado 2016

Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations

por Clare Samuelson, Stefan Radtke, Haiying Zhu, Mallory Llewellyn, Emily Fields, Savannah Cook, Meei-Li W. Huang, Keith R. Jerome, Hans-Peter Kiem, Olivier Humbert
Publicado 2021

Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy

por Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle
Publicado 2020

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation

por Lucrezia Colonna, Christopher W. Peterson, John B. Schell, Judith M. Carlson, Victor Tkachev, Melanie Brown, Alison Yu, Sowmya Reddy, Willi M. Obenza, Veronica Nelson, Patricia S. Polacino, Heather Mack, Shiu-Lok Hu, Katie Zeleski, Michelle Hoffman, Joe Olvera, Scott N. Furlan, Hengqi Zheng, Agne Taraseviciute, Daniel J. Hunt, Kayla Betz, Jennifer F. Lane, Keith Vogel, Charlotte E. Hotchkiss, Cassie Moats, Audrey Baldessari, Robert D. Murnane, Christopher English, Cliff A. Astley, Solomon Wangari, Brian Agricola, Joel Ahrens, Naoto Iwayama, Andrew May, Laurence Stensland, Meei-Li W. Huang, Keith R. Jerome, Hans-Peter Kiem, Leslie S. Kean
Publicado 2018