Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences

por Michael A. Skinnider, Chad W. Johnston, Mathusan Gunabalasingam, Nishanth J. Merwin, Agata M. Kieliszek, Robyn J. MacLellan, Haoxin Li, Michael R. M. Ranieri, Andrew L. H. Webster, My P. T. Cao, Annabelle Pfeifle, Norman Spencer, Q. Huy To, Dan Peter Wallace, Chris A. Dejong, Nathan A. Magarvey
Publicado 2020

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

por Yilong Zou, Michael J. Palte, Amy A. Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber
Publicado 2019

Metabolomic adaptations and correlates of survival to immune checkpoint blockade

por Haoxin Li, Kevin Bullock, Carino Gurjao, David Braun, Sachet A. Shukla, Dominick Bossé, Aly-Khan A. Lalani, Shuba Gopal, Chelsea Jin, Christine Horak, Megan Wind-Rotolo, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Eliezer M. Van Allen, Stuart L. Schreiber, F. Stephen Hodi, William R. Sellers, Levi A. Garraway, Clary B. Clish, Toni K. Choueiri, Marios Giannakis
Publicado 2019