The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway.

por Wakako Furuyama, Kyle Shifflett, Heinz Feldmann, Andrea Marzi
Publicado 2021

Antiviral Innate Responses Induced by VSV-EBOV Vaccination Contribute to Rapid Protection

por Andrea R. Menicucci, Allen Jankeel, Heinz Feldmann, Andrea Marzi, Ilhem Messaoudi
Publicado 2019

Transcriptomic analysis reveals a previously unknown role for CD8+ T-cells in rVSV-EBOV mediated protection

por Andrea R. Menicucci, Suhas Sureshchandra, Andrea Marzi, Heinz Feldmann, Ilhem Messaoudi
Publicado 2017

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo.

por Allison Groseth, Andrea Marzi, Thomas Hoenen, Astrid Herwig, Don Gardner, Stephan Becker, Hideki Ebihara, Heinz Feldmann
Publicado 2012

An upstream open reading frame modulates ebola virus polymerase translation and virus replication.

por Reed S Shabman, Thomas Hoenen, Allison Groseth, Omar Jabado, Jennifer M Binning, Gaya K Amarasinghe, Heinz Feldmann, Christopher F Basler
Publicado 2013

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

por Masfique Mehedi, Thomas Hoenen, Shelly Robertson, Stacy Ricklefs, Michael A Dolan, Travis Taylor, Darryl Falzarano, Hideki Ebihara, Stephen F Porcella, Heinz Feldmann
Publicado 2013

Antibody quality and protection from lethal Ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine.

por Joseph E Blaney, Andrea Marzi, Mallory Willet, Amy B Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, Matthias J Schnell
Publicado 2013

Oseltamivir Is Effective against 1918 Influenza Virus Infection of Macaques but Vulnerable to Escape

por Friederike Feldmann, Darwyn Kobasa, Carissa Embury-Hyatt, Allen Grolla, Tracy Taylor, Maki Kiso, Satoshi Kakugawa, Jason Gren, Steven M. Jones, Yoshihiro Kawaoka, Heinz Feldmann
Publicado 2019

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

por James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer
Publicado 2020

Biosafety Level-4 laboratories in Europe: opportunities for public health, diagnostics, and research.

por Carla Nisii, Concetta Castilletti, Hervé Raoul, Roger Hewson, David Brown, Robin Gopal, Markus Eickmann, Stephan Gunther, Ali Mirazimi, Tuija Koivula, Heinz Feldmann, Antonino Di Caro, Maria R Capobianchi, Giuseppe Ippolito
Publicado 2013

Influenza Virus A/Anhui/1/2013 (H7N9) Replicates Efficiently in the Upper and Lower Respiratory Tracts of Cynomolgus Macaques

por Emmie de Wit, Angela L. Rasmussen, Friederike Feldmann, Trenton Bushmaker, Cynthia Martellaro, Elaine Haddock, Atsushi Okumura, Sean C. Proll, Jean Chang, Don Gardner, Michael G. Katze, Vincent J. Munster, Heinz Feldmann
Publicado 2014

Differential Ability of Pandemic and Seasonal H1N1 Influenza A Viruses To Alter the Function of Human Neutrophils

por Natalia Malachowa, Brett Freedman, Daniel E. Sturdevant, Scott D. Kobayashi, Vinod Nair, Friederike Feldmann, Tregei Starr, Olivia Steele-Mortimer, John C. Kash, Jeffery K. Taubenberger, Heinz Feldmann, Frank R. DeLeo
Publicado 2018

Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

por Robert W. Cross, Zachary A. Bornholdt, Abhishek N. Prasad, Joan B. Geisbert, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Kevin Melody, Karla A. Fenton, Heinz Feldmann, Armand Sprecher, Larry Zeitlin, Thomas W. Geisbert
Publicado 2020

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.

por Cristian Cillóniz, Kyoko Shinya, Xinxia Peng, Marcus J Korth, Sean C Proll, Lauri D Aicher, Victoria S Carter, Jean H Chang, Darwyn Kobasa, Friedericke Feldmann, James E Strong, Heinz Feldmann, Yoshihiro Kawaoka, Michael G Katze
Publicado 2009

Purification of Crimean–Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis

por Boniface Pongombo Lombe, Hiroko Miyamoto, Takeshi Saito, Reiko Yoshida, Rashid Manzoor, Masahiro Kajihara, Masayuki Shimojima, Shuetsu Fukushi, Shigeru Morikawa, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Saijo, Qing Tang, Justin Masumu, David Hawman, Heinz Feldmann, Ayato Takada
Publicado 2021

Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

por Kyle Rosenke, Frederick Hansen, Benjamin Schwarz, Friederike Feldmann, Elaine Haddock, Rebecca Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, Heinz Feldmann, Michael A. Jarvis
Publicado 2021

Infection with MERS-CoV causes lethal pneumonia in the common marmoset.

por Darryl Falzarano, Emmie de Wit, Friederike Feldmann, Angela L Rasmussen, Atsushi Okumura, Xinxia Peng, Matthew J Thomas, Neeltje van Doremalen, Elaine Haddock, Lee Nagy, Rachel LaCasse, Tingting Liu, Jiang Zhu, Jason S McLellan, Dana P Scott, Michael G Katze, Heinz Feldmann, Vincent J Munster
Publicado 2014

Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques

por Kim J. Hasenkrug, Friederike Feldmann, Lara Myers, Mario L. Santiago, Kejun Guo, Bradley S. Barrett, Kaylee L. Mickens, Aaron Carmody, Atsushi Okumura, Deepashri Rao, Madison M. Collins, Ronald J. Messer, Jamie Lovaglio, Carl Shaia, Rebecca Rosenke, Neeltje van Doremalen, Chad Clancy, Greg Saturday, Patrick Hanley, Brian J. Smith, Kimberly Meade-White, W. Lesley Shupert, David W. Hawman, Heinz Feldmann
Publicado 2021