Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT

por Stephen Robson, Catherine McParlin, Helen Mossop, Mabel Lie, Cristina Fernandez-Garcia, Denise Howel, Ruth Graham, Laura Ternent, Alison Steel, Nicola Goudie, Afnan Nadeem, Julia Phillipson, Manjeet Shehmar, Nigel Simpson, Derek Tuffnell, Ian Campbell, Rew Williams, Margaret E O’Hara, Elaine McColl, Catherine Nelson-Piercy
Publicado 2021

The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel tr...

por Stephan Ursprung, Helen Mossop, Ferdia A. Gallagher, Evis Sala, Richard Skells, Jamal A. N. Sipple, Thomas J. Mitchell, Anita Chhabra, Kate Fife, Athena Matakidou, Gemma Young, Amanda Walker, Martin G. Thomas, Mireia Crispin Ortuzar, Mark Sullivan, Andrew Protheroe, Grenville Oades, Balaji Venugopal, Anne Y. Warren, John Stone, Tim Eisen, James Wason, Sarah J. Welsh, Grant D. Stewart
Publicado 2021