Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

por Kazuhide Asakawa, Hiroshi Handa, Koichi Kawakami
Publicado 2020

Adenine nucleotide translocator transports haem precursors into mitochondria.

por Motoki Azuma, Yasuaki Kabe, Chikanori Kuramori, Masao Kondo, Yuki Yamaguchi, Hiroshi Handa
Publicado 2008

PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates

por Nobuyuki Shimizu, Tomoko Asatsuma-Okumura, Junichi Yamamoto, Yuki Yamaguchi, Hiroshi Handa, Takumi Ito
Publicado 2021

BRCA1 degradation in response to mitochondrial damage in breast cancer cells

por Kana Miyahara, Naoharu Takano, Yumiko Yamada, Hiromi Kazama, Mayumi Tokuhisa, Hirotsugu Hino, Koji Fujita, Edward Barroga, Masaki Hiramoto, Hiroshi Handa, Masahiko Kuroda, Takashi Ishikawa, Keisuke Miyazawa
Publicado 2021

Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing.

por Hitomi Miyazaki, Ken Higashimoto, Yukari Yada, Takaho A Endo, Jafar Sharif, Toshiharu Komori, Masashi Matsuda, Yoko Koseki, Manabu Nakayama, Hidenobu Soejima, Hiroshi Handa, Haruhiko Koseki, Susumu Hirose, Kenichi Nishioka
Publicado 2013

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

por Yasuaki Kabe, Takanori Nakane, Ikko Koike, Tatsuya Yamamoto, Yuki Sugiura, Erisa Harada, Kenji Sugase, Tatsuro Shimamura, Mitsuyo Ohmura, Kazumi Muraoka, Ayumi Yamamoto, Takeshi Uchida, So Iwata, Yuki Yamaguchi, Elena Krayukhina, Masanori Noda, Hiroshi Handa, Koichiro Ishimori, Susumu Uchiyama, Takuya Kobayashi, Makoto Suematsu
Publicado 2016