Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing

par Kentaro Mochizuki, Jafar Sharif, Kenjiro Shirane, Kousuke Uranishi, Aaron B. Bogutz, Sanne M. Janssen, Ayumu Suzuki, Akihiko Okuda, Haruhiko Koseki, Matthew C. Lorincz
Publié 2021

Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing.

par Hitomi Miyazaki, Ken Higashimoto, Yukari Yada, Takaho A Endo, Jafar Sharif, Toshiharu Komori, Masashi Matsuda, Yoko Koseki, Manabu Nakayama, Hidenobu Soejima, Hiroshi Handa, Haruhiko Koseki, Susumu Hirose, Kenichi Nishioka
Publié 2013

Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes

par Hiroki Sugishita, Takashi Kondo, Shinsuke Ito, Manabu Nakayama, Nayuta Yakushiji-Kaminatsui, Eiryo Kawakami, Yoko Koseki, Yasuhide Ohinata, Jafar Sharif, Mio Harachi, Neil P. Blackledge, Robert J. Klose, Haruhiko Koseki
Publié 2021