The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD

por Qingan Sun, Xiaojun Li, Lisa M. Perez, Wanliang Shi, Ying Zhang, James C. Sacchettini
Publicado 2020

Perturbation of Cytochrome <italic toggle="yes">c</italic> Maturation Reveals Adaptability of the Respiratory Chain in <named-content content-type="genus-species">Mycobacterium tub...

por Jennifer L. Small, Sae Woong Park, Bavesh D. Kana, Thomas R. Ioerger, James C. Sacchettini, Sabine Ehrt
Publicado 2013

The Copper-Responsive RicR Regulon Contributes to <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Virulence

por Xiaoshan Shi, Richard A. Festa, Thomas R. Ioerger, Susan Butler-Wu, James C. Sacchettini, K. Heran Darwin, Marie I. Samanovic
Publicado 2014

A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide

por Adam N. Yadon, Kashmeel Maharaj, John H. Adamson, Yi-Pin Lai, James C. Sacchettini, Thomas R. Ioerger, Eric J. Rubin, Alexander S. Pym
Publicado 2017

Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

por Robert S. Jansen, Lungelo Mandyoli, Ryan Hughes, Shoko Wakabayashi, Jessica T. Pinkham, Bruna Selbach, Kristine M. Guinn, Eric J. Rubin, James C. Sacchettini, Kyu Y. Rhee
Publicado 2020

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

por Jared S. Mackenzie, Dirk A. Lamprecht, Rukaya Asmal, John H. Adamson, Khushboo Borah, Dany J. V. Beste, Bei Shi Lee, Kevin Pethe, Simon Rousseau, Inna Krieger, James C. Sacchettini, Joel N. Glasgow, Adrie J. C. Steyn
Publicado 2020