Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases

por Kalpana Raja, Matthew Patrick, James T. Elder, Lam C. Tsoi
Publicado 2017

IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis

por Nehal N. Mehta, Heather L. Teague, William R. Swindell, Yvonne Baumer, Nicole L. Ward, Xianying Xing, Brooke Baugous, Andrew Johnston, Aditya A. Joshi, Joanna Silverman, Drew H. Barnes, Liza Wolterink, Rajan P. Nair, Philip E. Stuart, Martin Playford, John J. Voorhees, Mrinal K. Sarkar, James T. Elder, Katherine Gallagher, Santhi K. Ganesh, Johann E. Gudjonsson
Publicado 2017

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide

por Philip E. Stuart, Lam C. Tsoi, Rajan P. Nair, Manju Ghosh, Madhulika Kabra, Pakeeza A. Shaiq, Ghazala K. Raja, Raheel Qamar, B.K. Thelma, Matthew T. Patrick, Anita Parihar, Sonam Singh, Sujay Khandpur, Uma Kumar, Michael Wittig, Frauke Degenhardt, Trilokraj Tejasvi, John J. Voorhees, Stephan Weidinger, Andre Franke, Goncalo R. Abecasis, Vinod K. Sharma, James T. Elder
Publicado 2022

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients

por Matthew T. Patrick, Philip E. Stuart, Kalpana Raja, Johann E. Gudjonsson, Trilokraj Tejasvi, Jingjing Yang, Vinod Chandran, Sayantan Das, Kristina Callis-Duffin, Eva Ellinghaus, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Hyun M. Kang, Gerald G. Krueger, Henry W. Lim, Proton Rahman, Cheryl F. Rosen, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, John J. Voorhees, Gonçalo R. Abecasis, Dafna D. Gladman, Rajan P. Nair, James T. Elder, Lam C. Tsoi
Publicado 2018

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

por Lam C. Tsoi, Philip E. Stuart, Chao Tian, Johann E. Gudjonsson, Sayantan Das, Matthew Zawistowski, Eva Ellinghaus, Jonathan N. Barker, Vinod Chandran, Nick Dand, Kristina Callis Duffin, Charlotta Enerbäck, Tõnu Esko, Andre Franke, Dafna D. Gladman, Per Hoffmann, Külli Kingo, Sulev Kõks, Gerald G. Krueger, Henry W. Lim, Andres Metspalu, Ulrich Mrowietz, Sören Mucha, Proton Rahman, Andre Reis, Trilokraj Tejasvi, Richard Trembath, John J. Voorhees, Stephan Weidinger, Michael Weichenthal, Xiaoquan Wen, Nicholas Eriksson, Hyun M. Kang, David A. Hinds, Rajan P. Nair, Gonçalo R. Abecasis, James T Elder
Publicado 2017