Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes

por Peiman Shooshtarizadeh, Anne Helness, Charles Vadnais, Nelleke Brouwer, Hugues Beauchemin, Riyan Chen, Halil Bagci, Frank J. T. Staal, Jean-François Coté, Tarik Möröy
Publicado 2019

GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

por Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy
Publicado 2021

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

por Leifu Chang, Jing Yang, Chang Hwa Jo, Andreas Boland, Ziguo Zhang, Stephen H. McLaughlin, Afnan Abu-Thuraia, Ryan C. Killoran, Matthew J. Smith, Jean-Francois Côté, David Barford
Publicado 2020

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

por Noumeira Hamoud, Viviane Tran, Takahiro Aimi, Wataru Kakegawa, Sylvie Lahaie, Marie-Pier Thibault, Ariane Pelletier, G. William Wong, In-San Kim, Artur Kania, Michisuke Yuzaki, Michel Bouvier, Jean-François Côté
Publicado 2018

GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1

por Charles Vadnais, Riyan Chen, Jennifer Fraszczak, Zhenbao Yu, Jonathan Boulais, Jordan Pinder, Daria Frank, Cyrus Khandanpour, Josée Hébert, Graham Dellaire, Jean-François Côté, Stéphane Richard, Alexandre Orthwein, Elliot Drobetsky, Tarik Möröy
Publicado 2018

A licensing step links AID to transcription elongation for mutagenesis in B cells

por Stephen P. Methot, Ludivine C. Litzler, Poorani Ganesh Subramani, Anil K. Eranki, Heather Fifield, Anne-Marie Patenaude, Julian C. Gilmore, Gabriel E. Santiago, Halil Bagci, Jean-François Côté, Mani Larijani, Ramiro E. Verdun, Javier M. Di Noia
Publicado 2018

CdGAP promotes prostate cancer metastasis by regulating epithelial-to-mesenchymal transition, cell cycle progression, and apoptosis

por Chahat Mehra, Ji-Hyun Chung, Yi He, Mónica Lara-Márquez, Marie-Anne Goyette, Nadia Boufaied, Véronique Barrès, Véronique Ouellet, Karl-Phillippe Guérard, Carine Delliaux, Fred Saad, Jacques Lapointe, Jean-François Côté, David P. Labbé, Nathalie Lamarche-Vane
Publicado 2021

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

por Afnan Abu-Thuraia, Marie-Anne Goyette, Jonathan Boulais, Carine Delliaux, Chloé Apcher, Céline Schott, Rony Chidiac, Halil Bagci, Marie-Pier Thibault, Dominique Davidson, Mathieu Ferron, André Veillette, Roger J. Daly, Anne-Claude Gingras, Jean-Philippe Gratton, Jean-François Côté
Publicado 2020

Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer

por Islam E. Elkholi, Massimo Di Iorio, Somayyeh Fahiminiya, Suzanna L. Arcand, HyeRim Han, Clara Nogué, Supriya Behl, Nancy Hamel, Sylvie Giroux, Manon de Ladurantaye, Olga Aleynikova, Walter H. Gotlieb, Jean-François Côté, François Rousseau, Patricia N. Tonin, Diane Provencher, Anne-Marie MesMasson, Mohammad R. Akbari, Barbara Rivera, William D. Foulkes
Publicado 2021