Using numerical modeling and simulation to assess the ethical burden in clinical trials and how it relates to the proportion of responders in a trial sample.

por Jean-Pierre Boissel, David Pérol, Hervé Décousus, Ingrid Klingmann, Marc Hommel
Publicado 2021

The global risk approach should be better applied in French hypertensive patients: a comparison between simulation and observation studies.

por Ivanny Marchant, Patrice Nony, Michel Cucherat, Jean-Pierre Boissel, S Randall Thomas, Theodora Bejan-Angoulvant, Alexandra Laugerotte, Riad Kahoul, François Gueyffier
Publicado 2011

Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials.

por Rémy Boussageon, Irène Supper, Theodora Bejan-Angoulvant, Nadir Kellou, Michel Cucherat, Jean-Pierre Boissel, Behrouz Kassai, Alain Moreau, François Gueyffier, Catherine Cornu
Publicado 2012

Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility

por Flora T. Musuamba, Ine Skottheim Rusten, Raphaëlle Lesage, Giulia Russo, Roberta Bursi, Luca Emili, Gaby Wangorsch, Efthymios Manolis, Kristin E. Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Cécile F. Rousseau, Emmanuelle M. Voisin, Rossana Alessandrello, Nuno Curado, Enrico Dall’ara, Blanca Rodriguez, Francesco Pappalardo, Liesbet Geris
Publicado 2021