STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors.

par Thiruganesh Ramasamy, Xucai Chen, Bin Qin, Daniel E Johnson, Jennifer R Grandis, Flordeliza S Villanueva
Publié 2020

Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance.

par Rachel A O'Keefe, Neil E Bhola, David S Lee, Daniel E Johnson, Jennifer R Grandis
Publié 2020

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

par Zhiyong Wang, Yusuke Goto, Michael M. Allevato, Victoria H. Wu, Robert Saddawi-Konefka, Mara Gilardi, Diego Alvarado, Bryan S. Yung, Aoife O’Farrell, Alfredo A. Molinolo, Umamaheswar Duvvuri, Jennifer R. Grandis, Joseph A. Califano, Ezra E. W. Cohen, J. Silvio Gutkind
Publié 2021

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

par Yvonne Y Li, Grace T. Y. Chung, Vivian W. Y. Lui, Ka-Fai To, Brigette B. Y. Ma, Chit Chow, John K, S. Woo, Kevin Y. Yip, Jeongsun Seo, Edwin P. Hui, Michael K. F. Mak, Maria Rusan, Nicole G. Chau, Yvonne Y. Y. Or, Marcus H. N. Law, Peggy P. Y. Law, Zoey W. Y. Liu, Hoi-Lam Ngan, Pok-Man Hau, Krista R. Verhoeft, Peony H. Y. Poon, Seong-Keun Yoo, Jong-Yeon Shin, Sau-Dan Lee, Samantha W. M. Lun, Lin Jia, Anthony W. H. Chan, Jason Y. K. Chan, Paul B. S. Lai, Choi-Yi Fung, Suet-Ting Hung, Lin Wang, Ann Margaret V. Chang, Simion I. Chiosea, Matthew L. Hedberg, Sai-Wah Tsao, Andrew C. van Hasselt, Anthony T. C. Chan, Jennifer R. Grandis, Peter S. Hammerman, Kwok-Wai Lo
Publié 2017