Intrinsically unstructured domain 3 of hepatitis C Virus NS5A forms a "fuzzy complex" with VAPB-MSP domain which carries ALS-causing mutations.

por Garvita Gupta, Haina Qin, Jianxing Song
Publicado 2012

RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils

por Yimei Lu, Liangzhong Lim, Jianxing Song
Publicado 2017

ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues

por Mei Dang, Liangzhong Lim, Jian Kang, Jianxing Song
Publicado 2021

Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain.

por Liangzhong Lim, Jiahai Shi, Yuguang Mu, Jianxing Song
Publicado 2014

Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain.

por Jiahai Shi, Nanyu Han, Liangzhong Lim, Shixiong Lua, J Sivaraman, Lushan Wang, Yuguang Mu, Jianxing Song
Publicado 2011