Dissection of the amyloid formation pathway in AL amyloidosis

por Pamina Kazman, Ramona M. Absmeier, Harald Engelhardt, Johannes Buchner
Publicado 2021

Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody design

por Hristo L. Svilenov, Julia Sacherl, Ulrike Protzer, Martin Zacharias, Johannes Buchner
Publicado 2021

A switch point in the molecular chaperone Hsp90 responding to client interaction

por Daniel Andreas Rutz, Qi Luo, Lee Freiburger, Tobias Madl, Ville R. I. Kaila, Michael Sattler, Johannes Buchner
Publicado 2018

FEBS Open Bio: past, present and future

por Duncan E. Wright, Félix M. Goñi, Mary Purton, László Fésüs, Johannes Buchner, John Mowbray, Miguel A. De la Rosa
Publicado 2021

Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble

por Moritz Mühlhofer, Carsten Peters, Thomas Kriehuber, Marina Kreuzeder, Pamina Kazman, Natalia Rodina, Bernd Reif, Martin Haslbeck, Sevil Weinkauf, Johannes Buchner
Publicado 2021

Structural and functional analysis of the DEAF-1 and BS69 MYND domains.

por Fatiha Kateb, Helene Perrin, Konstantinos Tripsianes, Peijian Zou, Roberta Spadaccini, Matthew Bottomley, Titus M Franzmann, Johannes Buchner, Stephane Ansieau, Michael Sattler
Publicado 2013

Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90

por Sophie L. Mader, Abraham Lopez, Jannis Lawatscheck, Qi Luo, Daniel A. Rutz, Ana P. Gamiz-Hernandez, Michael Sattler, Johannes Buchner, Ville R. I. Kaila
Publicado 2020

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range

por Hannah Girstmair, Franziska Tippel, Abraham Lopez, Katarzyna Tych, Frank Stein, Per Haberkant, Philipp Werner Norbert Schmid, Dominic Helm, Matthias Rief, Michael Sattler, Johannes Buchner
Publicado 2019

Author Correction: A methylated lysine is a switch point for conformational communication in the chaperone Hsp90

por Alexandra Rehn, Jannis Lawatscheck, Marie-Lena Jokisch, Sophie L. Mader, Qi Luo, Franziska Tippel, Birgit Blank, Klaus Richter, Kathrin Lang, Ville R. I. Kaila, Johannes Buchner
Publicado 2020

A methylated lysine is a switch point for conformational communication in the chaperone Hsp90

por Alexandra Rehn, Jannis Lawatscheck, Marie-Lena Jokisch, Sophie L. Mader, Qi Luo, Franziska Tippel, Birgit Blank, Klaus Richter, Kathrin Lang, Ville R. I. Kaila, Johannes Buchner
Publicado 2020

Breakdown of supersaturation barrier links protein folding to amyloid formation

por Masahiro Noji, Tatsushi Samejima, Keiichi Yamaguchi, Masatomo So, Keisuke Yuzu, Eri Chatani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yasushi Kawata, Kensuke Ikenaka, Hideki Mochizuki, József Kardos, Daniel E. Otzen, Vittorio Bellotti, Johannes Buchner, Yuji Goto
Publicado 2021

The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells

por Manuel Schuster, Leonie Schnell, Peter Feigl, Carina Birkhofer, Katharina Mohr, Maurice Roeder, Stefan Carle, Simon Langer, Franziska Tippel, Johannes Buchner, Gunter Fischer, Felix Hausch, Manfred Frick, Carsten Schwan, Klaus Aktories, Cordelia Schiene-Fischer, Holger Barth
Publicado 2017