The mutREAD method detects mutational signatures from low quantities of cancer DNA

par Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D. Eldridge, Simon Tavaré, Rebecca C. Fitzgerald
Publié 2020

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

par Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi, The Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Francesca D. Ciccarelli
Publié 2019

Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

par Xiaodun Li, Hayley E. Francies, Maria Secrier, Juliane Perner, Ahmad Miremadi, Núria Galeano-Dalmau, William J. Barendt, Laura Letchford, Genevieve M. Leyden, Emma K. Goffin, Andrew Barthorpe, Howard Lightfoot, Elisabeth Chen, James Gilbert, Ayesha Noorani, Ginny Devonshire, Lawrence Bower, Amber Grantham, Shona MacRae, Nicola Grehan, David C. Wedge, Rebecca C. Fitzgerald, Mathew J. Garnett
Publié 2018