Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candid...

por Beatriz Perdiguero, Carmen Elena Gómez, Mauro Di Pilato, Carlos Oscar S Sorzano, Julie Delaloye, Thierry Roger, Thierry Calandra, Giuseppe Pantaleo, Mariano Esteban
Publicado 2013

Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.

por Beatriz Perdiguero, Carmen Elena Gómez, Jose Luis Nájera, Carlos Oscar S Sorzano, Julie Delaloye, Rubén González-Sanz, Victoria Jiménez, Thierry Roger, Thierry Calandra, Giuseppe Pantaleo, Mariano Esteban
Publicado 2012

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

por Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Petrilli, Carmen E Gomez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Esteban, Thierry Calandra
Publicado 2009

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

por Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K Haddad, Esther D Quakkelaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Duhen, Rafick P Sékaly, Cornelis J M Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Publicado 2012