Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria

por José Carlos Santos, Dave Boucher, Larisa Kapinos Schneider, Benjamin Demarco, Marisa Dilucca, Kateryna Shkarina, Rosalie Heilig, Kaiwen W. Chen, Roderick Y. H. Lim, Petr Broz
Publicado 2020

Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.

por Elisabet Bjanes, Reyna Garcia Sillas, Rina Matsuda, Benjamin Demarco, Timothée Fettrelet, Alexandra A DeLaney, Opher S Kornfeld, Bettina L Lee, Eric M Rodríguez López, Daniel Grubaugh, Meghan A Wynosky-Dolfi, Naomi H Philip, Elise Krespan, Dorothy Tovar, Leonel Joannas, Daniel P Beiting, Jorge Henao-Mejia, Brian C Schaefer, Kaiwen W Chen, Petr Broz, Igor E Brodsky
Publicado 2021