Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

por Sonia Maciejewski, Joseph H. C. Nguyen, Fernando Gómez-Herreros, Felipe Cortés-Ledesma, Keith W. Caldecott, Bert L. Semler
Publicado 2016

TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription

por Fernando Gómez-Herreros, Guido Zagnoli-Vieira, Ioanna Ntai, María Isabel Martínez-Macías, Rhona M. Anderson, Andrés Herrero-Ruíz, Keith W. Caldecott
Publicado 2017

The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins

por Gabrielle J. Grundy, Stuart L. Rulten, Raquel Arribas-Bosacoma, Kathryn Davidson, Zuzanna Kozik, Antony W. Oliver, Laurence H. Pearl, Keith W. Caldecott
Publicado 2016

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.

por Fernando Gómez-Herreros, Rocío Romero-Granados, Zhihong Zeng, Alejandro Alvarez-Quilón, Cristina Quintero, Limei Ju, Lieve Umans, Liesbeth Vermeire, Danny Huylebroeck, Keith W Caldecott, Felipe Cortés-Ledesma
Publicado 2013

Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair

por Hana Hanzlikova, Evgeniia Prokhorova, Katerina Krejcikova, Zuzana Cihlarova, Ilona Kalasova, Jan Kubovciak, Jana Sachova, Richard Hailstone, Jan Brazina, Shereen Ghosh, Sebahattin Cirak, Joseph G. Gleeson, Ivan Ahel, Keith W. Caldecott
Publicado 2020

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2

por Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott
Publicado 2016