Dramatic activation of an antibody by a single amino acid change in framework

por Wei-Ching Liang, Jianping Yin, Patrick Lupardus, Jianhuan Zhang, Kelly M. Loyet, Jawahar Sudhamsu, Yan Wu
Publicado 2021

Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge

por Henry R. Maun, Rajesh Vij, Benjamin T. Walters, Ashley Morando, Janet K. Jackman, Ping Wu, Alberto Estevez, Xiaocheng Chen, Yvonne Franke, Michael T. Lipari, Mark S. Dennis, Daniel Kirchhofer, Claudio Ciferri, Kelly M. Loyet, Tangsheng Yi, Charles Eigenbrot, Robert A. Lazarus, James T. Koerber
Publicado 2020

Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate

por Kimberly K. Kajihara, Homer Pantua, Hilda Hernandez-Barry, Meredith Hazen, Kiran Deshmukh, Nancy Chiang, Rachana Ohri, Erick R. Castellanos, Lynn Martin, Marissa L. Matsumoto, Jian Payandeh, Kelly M. Storek, Kellen Schneider, Peter A. Smith, Michael F. T. Koehler, Siao Ping Tsai, Richard Vandlen, Kelly M. Loyet, Gerald Nakamura, Thomas Pillow, Dhaya Seshasayee, Sharookh B. Kapadia, Wouter L. W. Hazenbos
Publicado 2021