Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.

par Nicholas I Fleming, Kevin C Knower, Kyren A Lazarus, Peter J Fuller, Evan R Simpson, Colin D Clyne
Publié 2010

The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation.

par Ashwini L Chand, Dhilushi D Wijayakumara, Kevin C Knower, Kerrie A Herridge, Tamara L Howard, Kyren A Lazarus, Colin D Clyne
Publié 2012

Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations.

par Kevin C Knower, Sabine Kelly, Louisa M Ludbrook, Stefan Bagheri-Fam, Helena Sim, Pascal Bernard, Ryohei Sekido, Robin Lovell-Badge, Vincent R Harley
Publié 2011