The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner.

por Kristine Williams, Jesper Christensen, Juri Rappsilber, Anders Lærke Nielsen, Jens Vilstrup Johansen, Kristian Helin
Publicado 2014

A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence.

por Susanne Marije Kooistra, Lise Christine Rudkjær Nørgaard, Michael James Lees, Cornelia Steinhauer, Jens Vilstrup Johansen, Kristian Helin
Publicado 2014

MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells

por Iris Müller, Ann Sophie Moroni, Daria Shlyueva, Sudeep Sahadevan, Erwin M. Schoof, Aliaksandra Radzisheuskaya, Jonas W. Højfeldt, Tülin Tatar, Richard P. Koche, Chang Huang, Kristian Helin
Publicado 2021

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

por Sarah Cooper, Anne Grijzenhout, Elizabeth Underwood, Katia Ancelin, Tianyi Zhang, Tatyana B. Nesterova, Burcu Anil-Kirmizitas, Andrew Bassett, Susanne M. Kooistra, Karl Agger, Kristian Helin, Edith Heard, Neil Brockdorff
Publicado 2016

Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

por Hui Li, Qi Yao, Alberto Garcia Mariscal, Xudong Wu, Justus Hülse, Esben Pedersen, Kristian Helin, Ari Waisman, Caroline Vinkel, Simon Francis Thomsen, Alexandra Avgustinova, Salvador Aznar Benitah, Paola Lovato, Hanne Norsgaard, Mette Sidsel Mortensen, Lone Veng, Björn Rozell, Cord Brakebusch
Publicado 2018

Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.

por Lise Lotte Christensen, Anja Holm, Juha Rantala, Olli Kallioniemi, Mads H Rasmussen, Marie S Ostenfeld, Frederik Dagnaes-Hansen, Bodil Øster, Troels Schepeler, Heidi Tobiasen, Kasper Thorsen, Oliver M Sieber, Peter Gibbs, Philippe Lamy, Torben F Hansen, Torben F Hansen, Anders Jakobsen, Eva M Riising, Kristian Helin, Jan Lubinski, Rikke Hagemann-Madsen, Søren Laurberg, Torben F Ørntoft, Claus L Andersen
Publicado 2014

Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary

por Sarah H. Kim, Arnaud Da Cruz Paula, Thais Basili, Higinio Dopeso, Rui Bi, Fresia Pareja, Edaise M. da Silva, Rodrigo Gularte-Mérida, Zhen Sun, Sho Fujisawa, Caitlin G. Smith, Lorenzo Ferrando, Ana Paula Martins Sebastião, Yonina Bykov, Anqi Li, Catarina Silveira, Charles W. Ashley, Anthe Stylianou, Pier Selenica, Wesley R. Samore, Achim A. Jungbluth, Dmitriy Zamarin, Nadeem R. Abu-Rustum, Kristian Helin, Robert A. Soslow, Jorge S. Reis-Filho, Esther Oliva, Britta Weigelt
Publicado 2020