RAS transformation requires CUX1-dependent repair of oxidative DNA damage.

por Zubaidah M Ramdzan, Charles Vadnais, Ranjana Pal, Guillaume Vandal, Chantal Cadieux, Lam Leduy, Sayeh Davoudi, Laura Hulea, Lu Yao, Anthony N Karnezis, Marilène Paquet, David Dankort, Alain Nepveu
Publicado 2014

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway

por Mélissa Carbonneau, Laurence M. Gagné, Marie-Eve Lalonde, Marie-Anne Germain, Alena Motorina, Marie-Christine Guiot, Blandine Secco, Emma E. Vincent, Anthony Tumber, Laura Hulea, Jonathan Bergeman, Udo Oppermann, Russell G. Jones, Mathieu Laplante, Ivan Topisirovic, Kevin Petrecca, Marc-Étienne Huot, Frédérick A. Mallette
Publicado 2016

Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis

por Maxime Uriarte, Nadine Sen Nkwe, Roch Tremblay, Oumaima Ahmed, Clémence Messmer, Nazar Mashtalir, Haithem Barbour, Louis Masclef, Marion Voide, Claire Viallard, Salima Daou, Djaileb Abdelhadi, Daryl Ronato, Mohammadjavad Paydar, Anaïs Darracq, Karine Boulay, Nicolas Desjardins-Lecavalier, Przemyslaw Sapieha, Jean-Yves Masson, Mikhail Sergeev, Benjamin H. Kwok, Laura Hulea, Frédérick A. Mallette, Eric Milot, Bruno Larrivée, Hugo Wurtele, El Bachir Affar
Publicado 2021

PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis

por Slim Mzoughi, Jia Yi Fong, David Papadopoli, Cheryl M. Koh, Laura Hulea, Paolo Pigini, Federico Di Tullio, Giuseppe Andreacchio, Michal Marek Hoppe, Heike Wollmann, Diana Low, Matias J. Caldez, Yanfen Peng, Denis Torre, Julia N. Zhao, Oro Uchenunu, Gabriele Varano, Corina-Mihaela Motofeanu, Manikandan Lakshmanan, Shun Xie Teo, Cheng Mun Wun, Giovanni Perini, Soo Yong Tan, Chee Bing Ong, Muthafar Al-Haddawi, Ravisankar Rajarethinam, Susan Swee-Shan Hue, Soon Thye Lim, Choon Kiat Ong, Dachuan Huang, Siok-Bian Ng, Emily Bernstein, Dan Hasson, Keng Boon Wee, Philipp Kaldis, Anand Jeyasekharan, David Dominguez-sola, Ivan Topisirovic, Ernesto Guccione
Publicado 2020