Enhanced Cas12a multi-gene regulation using a CRISPR array separator

par Jens P Magnusson, Antonio Ray Rios, Lingling Wu, Lei S Qi
Publié 2021

Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system

par Nathan H. Kipniss, P. C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi
Publié 2017

YAP-independent mechanotransduction drives breast cancer progression

par Joanna Y. Lee, Jessica K. Chang, Antonia A. Dominguez, Hong-pyo Lee, Sungmin Nam, Julie Chang, Sushama Varma, Lei S. Qi, Robert B. West, Ovijit Chaudhuri
Publié 2019

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

par Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Lei S. Qi, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
Publié 2020

Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells

par Muneaki Nakamura, Prashanth Srinivasan, Michael Chavez, Matthew A. Carter, Antonia A. Dominguez, Marie La Russa, Matthew B. Lau, Timothy R. Abbott, Xiaoshu Xu, Dehua Zhao, Yuchen Gao, Nathan H. Kipniss, Christina D. Smolke, Joseph Bondy-Denomy, Lei S. Qi
Publié 2019

CRISPR-based genome editing in primary human pancreatic islet cells

par Romina J. Bevacqua, Xiaoqing Dai, Jonathan Y. Lam, Xueying Gu, Mollie S. H. Friedlander, Krissie Tellez, Irene Miguel-Escalada, Silvia Bonàs-Guarch, Goutham Atla, Weichen Zhao, Seung Hyun Kim, Antonia A. Dominguez, Lei S. Qi, Jorge Ferrer, Patrick E. MacDonald, Seung K. Kim
Publié 2021

Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers

par Zhifen Yang, Lingyu Li, Ahu Turkoz, Pohan Chen, Rona Harari-Steinfeld, Maggie Bobbin, Ofir Stefanson, Hana Choi, Violena Pietrobon, Bennett Alphson, Angshumala Goswami, Vitaly Balan, Alper Kearney, Dharmesh Patel, Jin Yang, Damla Inel, Veena Vinod, Alessandra Cesano, Bing Wang, Kyung-Ho Roh, Lei S. Qi, Francesco M. Marincola
Publié 2021