Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.

por Diana Machado, Isabel Couto, João Perdigão, Liliana Rodrigues, Isabel Portugal, Pedro Baptista, Bruno Veigas, Leonard Amaral, Miguel Viveiros
Publicado 2012

The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis.

por Dick van Soolingen, Rogelio Hernandez-Pando, Hector Orozco, Diana Aguilar, Cecile Magis-Escurra, Leonard Amaral, Jakko van Ingen, Martin J Boeree
Publicado 2010

Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

por Mihail Lucian Pascu, Balazs Danko, Ana Martins, Nikoletta Jedlinszki, Tatiana Alexandru, Viorel Nastasa, Mihai Boni, Andra Militaru, Ionut Relu Andrei, Angela Staicu, Attila Hunyadi, Seamus Fanning, Leonard Amaral
Publicado 2013