Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.

par Diana Machado, Isabel Couto, João Perdigão, Liliana Rodrigues, Isabel Portugal, Pedro Baptista, Bruno Veigas, Leonard Amaral, Miguel Viveiros
Publié 2012

The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis.

par Dick van Soolingen, Rogelio Hernandez-Pando, Hector Orozco, Diana Aguilar, Cecile Magis-Escurra, Leonard Amaral, Jakko van Ingen, Martin J Boeree
Publié 2010

Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

par Mihail Lucian Pascu, Balazs Danko, Ana Martins, Nikoletta Jedlinszki, Tatiana Alexandru, Viorel Nastasa, Mihai Boni, Andra Militaru, Ionut Relu Andrei, Angela Staicu, Attila Hunyadi, Seamus Fanning, Leonard Amaral
Publié 2013