APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesic...

por Dolores Del Prete, Franco Lombino, Xinran Liu, Luciano D'Adamio, Luciano D'Adamio
Publicado 2014

An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.

por Franco Lombino, Fabrizio Biundo, Robert Tamayev, Ottavio Arancio, Luciano D'Adamio, Luciano D'Adamio
Publicado 2013