Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

par Yi Yu, Thomas C. Leete, David A. Born, Lauren Young, Luis A. Barrera, Seung-Joo Lee, Holly A. Rees, Giuseppe Ciaramella, Nicole M. Gaudelli
Publié 2020

Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

par Josh Tycko, Luis A. Barrera, Nicholas C. Huston, Ari E. Friedland, Xuebing Wu, Jonathan S. Gootenberg, Omar O. Abudayyeh, Vic E. Myer, Christopher J. Wilson, Patrick D. Hsu
Publié 2018

Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

par Josh Tycko, Luis A. Barrera, Nicholas C. Huston, Ari E. Friedland, Xuebing Wu, Jonathan S. Gootenberg, Omar O. Abudayyeh, Vic E. Myer, Christopher J. Wilson, Patrick D. Hsu
Publié 2018

Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus

par Anne Bothmer, Tanushree Phadke, Luis A. Barrera, Carrie M Margulies, Christina S. Lee, Frank Buquicchio, Sean Moss, Hayat S. Abdulkerim, William Selleck, Hariharan Jayaram, Vic E. Myer, Cecilia Cotta-Ramusino
Publié 2017