Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.

par Wu-Lin Charng, Shinya Yamamoto, Manish Jaiswal, Vafa Bayat, Bo Xiong, Ke Zhang, Hector Sandoval, Gabriela David, Stephen Gibbs, Hsiang-Chih Lu, Kuchuan Chen, Nikos Giagtzoglou, Hugo J Bellen
Publié 2014

Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.

par Bo Xiong, Vafa Bayat, Manish Jaiswal, Ke Zhang, Hector Sandoval, Wu-Lin Charng, Tongchao Li, Gabriela David, Lita Duraine, Yong-Qi Lin, G Gregory Neely, Shinya Yamamoto, Hugo J Bellen
Publié 2012

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.

par Shiuan Wang, Kai Li Tan, Melina A Agosto, Bo Xiong, Shinya Yamamoto, Hector Sandoval, Manish Jaiswal, Vafa Bayat, Ke Zhang, Wu-Lin Charng, Gabriela David, Lita Duraine, Kartik Venkatachalam, Theodore G Wensel, Hugo J Bellen
Publié 2014

Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans.

par Vafa Bayat, Isabelle Thiffault, Manish Jaiswal, Martine Tétreault, Taraka Donti, Florin Sasarman, Geneviève Bernard, Julie Demers-Lamarche, Marie-Josée Dicaire, Jean Mathieu, Michel Vanasse, Jean-Pierre Bouchard, Marie-France Rioux, Charles M Lourenco, Zhihong Li, Claire Haueter, Eric A Shoubridge, Brett H Graham, Bernard Brais, Hugo J Bellen
Publié 2012