Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4

by Noelia Fradejas-Villar, Wenchao Zhao, Uschi Reuter, Michael Doengi, Irina Ingold, Simon Bohleber, Marcus Conrad, Ulrich Schweizer
Published 2021

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

by Jonathan Muri, Sebastian Heer, Mai Matsushita, Lea Pohlmeier, Luigi Tortola, Tobias Fuhrer, Marcus Conrad, Nicola Zamboni, Jan Kisielow, Manfred Kopf
Published 2018

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

by Alexander Beatty, Tanu Singh, Yulia Y. Tyurina, Vladimir A. Tyurin, Svetlana Samovich, Emmanuelle Nicolas, Kristen Maslar, Yan Zhou, Kathy Q. Cai, Yinfei Tan, Sebastian Doll, Marcus Conrad, Aravind Subramanian, Hülya Bayır, Valerian E. Kagan, Ulrike Rennefahrt, Jeffrey R. Peterson
Published 2021

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

by Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mässenhausen, Nadia Zamora Gonzalez, Francesca Maremonti, Florian Gembardt, Nina Himmerkus, Markus Latk, Sophie Locke, Julian Marschner, Wenjun Li, Spencer Short, Sebastian Doll, Irina Ingold, Bettina Proneth, Christoph Daniel, Nazanin Kabgani, Rafael Kramann, Stephen Motika, Paul J. Hergenrother, Stefan R. Bornstein, Christian Hugo, Jan Ulrich Becker, Kerstin Amann, Hans-Joachim Anders, Daniel Kreisel, Derek Pratt, Michael Gütschow, Marcus Conrad, Andreas Linkermann
Published 2021

In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model

by Ilya V. Kelmanson, Arina G. Shokhina, Daria A. Kotova, Matvei S. Pochechuev, Alexandra D. Ivanova, Alexander I. Kostyuk, Anastasiya S. Panova, Anastasia A. Borodinova, Maxim A. Solotenkov, Evgeny A. Stepanov, Roman I. Raevskii, Aleksandr A. Moshchenko, Valeriy V. Pak, Yulia G. Ermakova, Gijsbert J.C. van Belle, Viktor Tarabykin, Pavel M. Balaban, Ilya V. Fedotov, Andrei B. Fedotov, Marcus Conrad, Ivan Bogeski, Dörthe M. Katschinski, Thorsten R. Doeppner, Mathias Bähr, Aleksei M. Zheltikov, Dmitry S. Bilan, Vsevolod V. Belousov
Published 2021