Refining the Balance of Attenuation and Immunogenicity of Respiratory Syncytial Virus by Targeted Codon Deoptimization of Virulence Genes

por Jia Meng, Sujin Lee, Anne L. Hotard, Martin L. Moore
Publicado 2014

A Critical Phenylalanine Residue in the Respiratory Syncytial Virus Fusion Protein Cytoplasmic Tail Mediates Assembly of Internal Viral Proteins into Viral Filaments and Particles

por Fyza Y. Shaikh, Reagan G. Cox, Aaron W. Lifland, Anne L. Hotard, John V. Williams, Martin L. Moore, Philip J. Santangelo, James E. Crowe
Publicado 2012

A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

por Sujin Lee, Minh Trang Nguyen, Michael G. Currier, Joe B. Jenkins, Elizabeth A. Strobert, Adriana E. Kajon, Ranjna Madan-Lala, Yury A. Bochkov, James E. Gern, Krishnendu Roy, Xiaoyan Lu, Dean D. Erdman, Paul Spearman, Martin L. Moore
Publicado 2016

Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein

por Daiyin Tian, Michael B. Battles, Syed M. Moin, Man Chen, Kayvon Modjarrad, Azad Kumar, Masaru Kanekiyo, Kevin W. Graepel, Noor M. Taher, Anne L. Hotard, Martin L. Moore, Min Zhao, Zi-Zheng Zheng, Ning-Shao Xia, Jason S. McLellan, Barney S. Graham
Publicado 2017

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

por Christopher C. Stobart, Christina A. Rostad, Zunlong Ke, Rebecca S. Dillard, Cheri M. Hampton, Joshua D. Strauss, Hong Yi, Anne L. Hotard, Jia Meng, Raymond J. Pickles, Kaori Sakamoto, Sujin Lee, Michael G. Currier, Syed M. Moin, Barney S. Graham, Marina S. Boukhvalova, Brian E. Gilbert, Jorge C. G. Blanco, Pedro A. Piedra, Elizabeth R. Wright, Martin L. Moore
Publicado 2016