Modeling of lung phenotype of Hermansky–Pudlak syndrome type I using patient-specific iPSCs

por Takahiro Suezawa, Shuhei Kanagaki, Yohei Korogi, Kazuhisa Nakao, Toyohiro Hirai, Koji Murakami, Masatoshi Hagiwara, Shimpei Gotoh
Publicado 2021

Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia

por Masahiko Ajiro, Tomonari Awaya, Young Jin Kim, Kei Iida, Masatsugu Denawa, Nobuo Tanaka, Ryo Kurosawa, Shingo Matsushima, Saiko Shibata, Tetsunori Sakamoto, Rolenz Studer, Adrian R. Krainer, Masatoshi Hagiwara
Publicado 2021

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer

por Simon Uzor, Sean R. Porazinski, Ling Li, Bethany Clark, Masahiko Ajiro, Kei Iida, Masatoshi Hagiwara, Abdullah A. Alqasem, Claire M. Perks, Ian D. Wilson, Sebastian Oltean, Michael R. Ladomery
Publicado 2021

Selective inhibition of the kinase DYRK1A by targeting its folding process

por Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka, Teikichi Ikura, Nobutoshi Ito, Hiroshi Shibuya, Takamitsu Hosoya, Masatoshi Hagiwara
Publicado 2016