Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice.

par M Ujue Latasa, Carmen Gil-Puig, Maite G Fernández-Barrena, Carlos M Rodríguez-Ortigosa, Jesús M Banales, Raquel Urtasun, Saioa Goñi, Miriam Méndez, Sara Arcelus, Nerea Juanarena, Juan A Recio, Sophie Lotersztajn, Jesús Prieto, Carmen Berasain, Fernando J Corrales, Jon Lecanda, Matías A Avila
Publié 2010

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

par Edurne San José-Enériz, Xabier Agirre, Obdulia Rabal, Amaia Vilas-Zornoza, Juan A. Sanchez-Arias, Estibaliz Miranda, Ana Ugarte, Sergio Roa, Bruno Paiva, Ander Estella-Hermoso de Mendoza, Rosa María Alvarez, Noelia Casares, Victor Segura, José I. Martín-Subero, François-Xavier Ogi, Pierre Soule, Clara M. Santiveri, Ramón Campos-Olivas, Giancarlo Castellano, Maite Garcia Fernandez de Barrena, Juan Roberto Rodriguez-Madoz, Maria José García-Barchino, Juan Jose Lasarte, Matias A Avila, Jose Angel Martinez-Climent, Julen Oyarzabal, Felipe Prosper
Publié 2017

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

par Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevilla, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller
Publié 2019