Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

par Hashim Ali, Miguel Mano, Luca Braga, Asma Naseem, Bruna Marini, Diem My Vu, Chiara Collesi, Germana Meroni, Marina Lusic, Mauro Giacca
Publié 2019

Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner

par Monika M. Gladka, Arwa Kohela, Bas Molenaar, Danielle Versteeg, Lieneke Kooijman, Jantine Monshouwer-Kloots, Veerle Kremer, Harmjan R. Vos, Manon M. H. Huibers, Jody J. Haigh, Danny Huylebroeck, Reinier A. Boon, Mauro Giacca, Eva van Rooij
Publié 2021

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction

par Serena Zacchigna, Valentina Martinelli, Silvia Moimas, Andrea Colliva, Marco Anzini, Andrea Nordio, Alessia Costa, Michael Rehman, Simone Vodret, Cristina Pierro, Giulia Colussi, Lorena Zentilin, Maria Ines Gutierrez, Ellen Dirkx, Carlin Long, Gianfranco Sinagra, David Klatzmann, Mauro Giacca
Publié 2018

Identification of HSP90 inhibitors as a novel class of senolytics

par Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J. McGowan, Yi Zhu, Robert W. Brooks, Diego Grassi, Siobhan Q. Gregg, Jennifer L. Stripay, Akaitz Dorronsoro, Lana Corbo, Priscilla Tang, Christina Bukata, Nadja Ring, Mauro Giacca, Xuesen Li, Tamara Tchkonia, James L. Kirkland, Laura J. Niedernhofer, Paul D. Robbins
Publié 2017

A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration

par Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid el Azzouzi, Ryan J. Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana S. Nascimento, Paula A. da Costa Martins, Jop H. van Berlo, Serena Zacchigna, Mauro Giacca, Leon J. De Windt
Publié 2021

MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy

par Elena Sommariva, Yuri D’Alessandra, Floriana Maria Farina, Michela Casella, Fabio Cattaneo, Valentina Catto, Mattia Chiesa, Ilaria Stadiotti, Silvia Brambilla, Antonio Dello Russo, Corrado Carbucicchio, Giulia Vettor, Daniela Riggio, Maria Teresa Sandri, Andrea Barbuti, Gianluca Vernillo, Manuela Muratori, Matteo Dal Ferro, Gianfranco Sinagra, Silvia Moimas, Mauro Giacca, Gualtiero Ivanoe Colombo, Giulio Pompilio, Claudio Tondo
Publié 2017

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

par Clemens Gutmann, Kaloyan Takov, Sean A. Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark JW. McPhail, Kevin O’Gallagher, Lukas E. Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F. Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J. Doores, Jonathan D. Edgeworth, Ajay M. Shah, Stefan R. Bornstein, Torsten Tonn, Adrian C. Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr
Publié 2021