Genome-wide comparative analyses of correlated and uncorrelated phenotypes identify major pleiotropic variants in dairy cattle

por Ruidong Xiang, Iona M. MacLeod, Sunduimijid Bolormaa, Michael E. Goddard
Publicado 2017

Quantifying genetic heterogeneity between continental populations for human height and body mass index

por Jing Guo, Andrew Bakshi, Ying Wang, Longda Jiang, Loic Yengo, Michael E. Goddard, Peter M. Visscher, Jian Yang
Publicado 2021

Mutant alleles differentially shape fitness and other complex traits in cattle

por Ruidong Xiang, Ed J. Breen, Sunduimijid Bolormaa, Christy J. Vander Jagt, Amanda J. Chamberlain, Iona M. Macleod, Michael E. Goddard
Publicado 2021

Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations

por Ruidong Xiang, Iona M. MacLeod, Hans D. Daetwyler, Gerben de Jong, Erin O’Connor, Chris Schrooten, Amanda J. Chamberlain, Michael E. Goddard
Publicado 2021

Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals

por Kathryn E. Kemper, Loic Yengo, Zhili Zheng, Abdel Abdellaoui, Matthew C. Keller, Michael E. Goddard, Naomi R. Wray, Jian Yang, Peter M. Visscher
Publicado 2021

Widespread signatures of natural selection across human complex traits and functional genomic categories

por Jian Zeng, Angli Xue, Longda Jiang, Luke R. Lloyd-Jones, Yang Wu, Huanwei Wang, Zhili Zheng, Loic Yengo, Kathryn E. Kemper, Michael E. Goddard, Naomi R. Wray, Peter M. Visscher, Jian Yang
Publicado 2021

Improved polygenic prediction by Bayesian multiple regression on summary statistics

por Luke R. Lloyd-Jones, Jian Zeng, Julia Sidorenko, Loïc Yengo, Gerhard Moser, Kathryn E. Kemper, Huanwei Wang, Zhili Zheng, Reedik Magi, Tõnu Esko, Andres Metspalu, Naomi R. Wray, Michael E. Goddard, Jian Yang, Peter M. Visscher
Publicado 2019