PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.

par Nikolaus Thuille, Katarzyna Wachowicz, Natascha Hermann-Kleiter, Sandra Kaminski, Friedrich Fresser, Christina Lutz-Nicoladoni, Michael Leitges, Margot Thome, Ramin Massoumi, Gottfried Baier
Publié 2013

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.

par Romy Walser, John E Burke, Elena Gogvadze, Thomas Bohnacker, Xuxiao Zhang, Daniel Hess, Peter Küenzi, Michael Leitges, Emilio Hirsch, Roger L Williams, Muriel Laffargue, Matthias P Wymann
Publié 2013