Transcriptomic Changes Highly Similar to Alzheimer’s Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging

par Shouneng Peng, Shouneng Peng, Shouneng Peng, Lu Zeng, Lu Zeng, Lu Zeng, Jean-Vianney Haure-Mirande, Minghui Wang, Minghui Wang, Minghui Wang, Derek M. Huffman, Derek M. Huffman, Derek M. Huffman, Vahram Haroutunian, Vahram Haroutunian, Vahram Haroutunian, Michelle E. Ehrlich, Michelle E. Ehrlich, Michelle E. Ehrlich, Bin Zhang, Bin Zhang, Bin Zhang, Zhidong Tu, Zhidong Tu, Zhidong Tu
Publié 2021

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

par Mads E. Hauberg, Jordi Creus-Muncunill, Jaroslav Bendl, Alexey Kozlenkov, Biao Zeng, Chuhyon Corwin, Sarah Chowdhury, Harald Kranz, Yasmin L. Hurd, Michael Wegner, Anders D. Børglum, Stella Dracheva, Michelle E. Ehrlich, John F. Fullard, Panos Roussos
Publié 2020

Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease

par Noam D. Beckmann, Wei-Jye Lin, Minghui Wang, Ariella T. Cohain, Alexander W. Charney, Pei Wang, Weiping Ma, Ying-Chih Wang, Cheng Jiang, Mickael Audrain, Phillip H. Comella, Amanda K. Fakira, Siddharth P. Hariharan, Gillian M. Belbin, Kiran Girdhar, Allan I. Levey, Nicholas T. Seyfried, Eric B. Dammer, Duc Duong, James J. Lah, Jean-Vianney Haure-Mirande, Ben Shackleton, Tomas Fanutza, Robert Blitzer, Eimear Kenny, Jun Zhu, Vahram Haroutunian, Pavel Katsel, Sam Gandy, Zhidong Tu, Michelle E. Ehrlich, Bin Zhang, Stephen R. Salton, Eric E. Schadt
Publié 2020