Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations.

por Guillem Portella, Federica Battistini, Modesto Orozco
Publicado 2013

Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations

por Laura Orellana, Ozge Yoluk, Oliver Carrillo, Modesto Orozco, Erik Lindahl
Publicado 2016

Defining the nature of thermal intermediate in 3 state folding proteins: apoflavodoxin, a study case.

por Rebeca García-Fandiño, Pau Bernadó, Sara Ayuso-Tejedor, Javier Sancho, Modesto Orozco
Publicado 2012

The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function.

por Federica Battistini, Pablo D Dans, Montserrat Terrazas, Chiara L Castellazzi, Guillem Portella, Mireia Labrador, Núria Villegas, Isabelle Brun-Heath, Carlos González, Modesto Orozco
Publicado 2021

The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function

por Federica Battistini, Pablo D. Dans, Montserrat Terrazas, Chiara L. Castellazzi, Guillem Portella, Mireia Labrador, Núria Villegas, Isabelle Brun-Heath, Carlos González, Modesto Orozco
Publicado 2021

Bioactivity descriptors for uncharacterized chemical compounds

por Martino Bertoni, Miquel Duran-Frigola, Pau Badia-i-Mompel, Eduardo Pauls, Modesto Orozco-Ruiz, Oriol Guitart-Pla, Víctor Alcalde, Víctor M. Diaz, Antoni Berenguer-Llergo, Isabelle Brun-Heath, Núria Villegas, Antonio García de Herreros, Patrick Aloy
Publicado 2021

Impact of DNA methylation on 3D genome structure

por Diana Buitrago, Mireia Labrador, Juan Pablo Arcon, Rafael Lema, Oscar Flores, Anna Esteve-Codina, Julie Blanc, Nuria Villegas, David Bellido, Marta Gut, Pablo D. Dans, Simon C. Heath, Ivo G. Gut, Isabelle Brun Heath, Modesto Orozco
Publicado 2021

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

por Albert Escobedo, Busra Topal, Micha B. A. Kunze, Juan Aranda, Giulio Chiesa, Daniele Mungianu, Ganeko Bernardo-Seisdedos, Bahareh Eftekharzadeh, Margarida Gairí, Roberta Pierattelli, Isabella C. Felli, Tammo Diercks, Oscar Millet, Jesús García, Modesto Orozco, Ramon Crehuet, Kresten Lindorff-Larsen, Xavier Salvatella
Publicado 2019

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

por Amparo Garcia-Lopez, Francesca Tessaro, Hendrik R. A. Jonker, Anna Wacker, Christian Richter, Arnaud Comte, Nikolaos Berntenis, Roland Schmucki, Klas Hatje, Olivier Petermann, Gianpaolo Chiriano, Remo Perozzo, Daniel Sciarra, Piotr Konieczny, Ignacio Faustino, Guy Fournet, Modesto Orozco, Ruben Artero, Friedrich Metzger, Martin Ebeling, Peter Goekjian, Benoît Joseph, Harald Schwalbe, Leonardo Scapozza
Publicado 2018