Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations.

by Guillem Portella, Federica Battistini, Modesto Orozco
Published 2013

Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations

by Laura Orellana, Ozge Yoluk, Oliver Carrillo, Modesto Orozco, Erik Lindahl
Published 2016

Defining the nature of thermal intermediate in 3 state folding proteins: apoflavodoxin, a study case.

by Rebeca García-Fandiño, Pau Bernadó, Sara Ayuso-Tejedor, Javier Sancho, Modesto Orozco
Published 2012

The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function.

by Federica Battistini, Pablo D Dans, Montserrat Terrazas, Chiara L Castellazzi, Guillem Portella, Mireia Labrador, Núria Villegas, Isabelle Brun-Heath, Carlos González, Modesto Orozco
Published 2021

The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function

by Federica Battistini, Pablo D. Dans, Montserrat Terrazas, Chiara L. Castellazzi, Guillem Portella, Mireia Labrador, Núria Villegas, Isabelle Brun-Heath, Carlos González, Modesto Orozco
Published 2021

Bioactivity descriptors for uncharacterized chemical compounds

by Martino Bertoni, Miquel Duran-Frigola, Pau Badia-i-Mompel, Eduardo Pauls, Modesto Orozco-Ruiz, Oriol Guitart-Pla, Víctor Alcalde, Víctor M. Diaz, Antoni Berenguer-Llergo, Isabelle Brun-Heath, Núria Villegas, Antonio García de Herreros, Patrick Aloy
Published 2021

Impact of DNA methylation on 3D genome structure

by Diana Buitrago, Mireia Labrador, Juan Pablo Arcon, Rafael Lema, Oscar Flores, Anna Esteve-Codina, Julie Blanc, Nuria Villegas, David Bellido, Marta Gut, Pablo D. Dans, Simon C. Heath, Ivo G. Gut, Isabelle Brun Heath, Modesto Orozco
Published 2021

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

by Albert Escobedo, Busra Topal, Micha B. A. Kunze, Juan Aranda, Giulio Chiesa, Daniele Mungianu, Ganeko Bernardo-Seisdedos, Bahareh Eftekharzadeh, Margarida Gairí, Roberta Pierattelli, Isabella C. Felli, Tammo Diercks, Oscar Millet, Jesús García, Modesto Orozco, Ramon Crehuet, Kresten Lindorff-Larsen, Xavier Salvatella
Published 2019

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

by Amparo Garcia-Lopez, Francesca Tessaro, Hendrik R. A. Jonker, Anna Wacker, Christian Richter, Arnaud Comte, Nikolaos Berntenis, Roland Schmucki, Klas Hatje, Olivier Petermann, Gianpaolo Chiriano, Remo Perozzo, Daniel Sciarra, Piotr Konieczny, Ignacio Faustino, Guy Fournet, Modesto Orozco, Ruben Artero, Friedrich Metzger, Martin Ebeling, Peter Goekjian, Benoît Joseph, Harald Schwalbe, Leonardo Scapozza
Published 2018