Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3

por Yoshinori Tsukumo, Tommy Alain, Bruno D. Fonseca, Robert Nadon, Nahum Sonenberg
Publicado 2016

The translational landscape of ground state pluripotency

por Yaser Atlasi, Seyed Mehdi Jafarnejad, Christos G. Gkogkas, Michiel Vermeulen, Nahum Sonenberg, Hendrik G. Stunnenberg
Publicado 2020

LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction

por Jay Penney, Kazuya Tsurudome, Edward H. Liao, Grant Kauwe, Lindsay Gray, Akiko Yanagiya, Mario R. Calderon, Nahum Sonenberg, A. Pejmun Haghighi
Publicado 2016

Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3.

por Marcelo Marcet-Palacios, Brenda Lee Duggan, Irene Shostak, Michele Barry, Tracy Geskes, John A Wilkins, Akiko Yanagiya, Nahum Sonenberg, R Chris Bleackley
Publicado 2011

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs

por Aitor Garzia, Seyed Mehdi Jafarnejad, Cindy Meyer, Clément Chapat, Tasos Gogakos, Pavel Morozov, Mehdi Amiri, Maayan Shapiro, Henrik Molina, Thomas Tuschl, Nahum Sonenberg
Publicado 2017

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition

por Jennifer E. Dawson, Alaji Bah, Zhenfu Zhang, Robert M. Vernon, Hong Lin, P. Andrew Chong, Manasvi Vanama, Nahum Sonenberg, Claudiu C. Gradinaru, Julie D. Forman-Kay
Publicado 2020

Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing

por Manuel Blandino-Rosano, Rebecca Barbaresso, Margarita Jimenez-Palomares, Nadejda Bozadjieva, Joao Pedro Werneck-de-Castro, Masayuki Hatanaka, Raghavendra G. Mirmira, Nahum Sonenberg, Ming Liu, Markus A. Rüegg, Michael N. Hall, Ernesto Bernal-Mizrachi
Publicado 2017

BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models

por John Maringa Githaka, Namita Tripathi, Raven Kirschenman, Namrata Patel, Vrajesh Pandya, David A. Kramer, Rachel Montpetit, Lin Fu Zhu, Nahum Sonenberg, Richard P. Fahlman, Nika N. Danial, D. Alan Underhill, Ing Swie Goping
Publicado 2021

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E

por Argel Aguilar-Valles, Nabila Haji, Danilo De Gregorio, Edna Matta-Camacho, Mohammad J. Eslamizade, Jelena Popic, Vijendra Sharma, Ruifeng Cao, Christoph Rummel, Arnaud Tanti, Shane Wiebe, Nicolas Nuñez, Stefano Comai, Robert Nadon, Giamal Luheshi, Naguib Mechawar, Gustavo Turecki, Jean-Claude Lacaille, Gabriella Gobbi, Nahum Sonenberg
Publicado 2018

A threonyl-tRNA synthetase-mediated translation initiation machinery

por Seung Jae Jeong, Shinhye Park, Loi T. Nguyen, Jungwon Hwang, Eun-Young Lee, Hoi-Khoanh Giong, Jeong-Soo Lee, Ina Yoon, Ji-Hyun Lee, Jong Hyun Kim, Hoi Kyoung Kim, Doyeun Kim, Won Suk Yang, Seon-Young Kim, Chan Yong Lee, Kweon Yu, Nahum Sonenberg, Myung Hee Kim, Sunghoon Kim
Publicado 2019