Evidence of selection on splicing-associated loci in human populations and relevance to disease loci mapping

por Eric R. Gamazon, Anuar Konkashbaev, Eske M. Derks, Nancy J. Cox, Younghee Lee
Publicado 2017

Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus.

por Jessica A Belser, Akila Jayaraman, Rahul Raman, Claudia Pappas, Hui Zeng, Nancy J Cox, Jacqueline M Katz, Ram Sasisekharan, Terrence M Tumpey
Publicado 2011

Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles

por Emily J. Ross, Emily R. Gordon, Hanna Sothers, Roshan Darji, Oakley Baron, Dustin Haithcock, Balabhaskar Prabhakarpandian, Kapil Pant, Richard M. Myers, Sara J. Cooper, Nancy J. Cox
Publicado 2021

Use of Highly Pathogenic Avian Influenza A(H5N1) Gain-Of-Function Studies for Molecular-Based Surveillance and Pandemic Preparedness

por C. Todd Davis, Li-Mei Chen, Claudia Pappas, James Stevens, Terrence M. Tumpey, Larisa V. Gubareva, Jacqueline M. Katz, Julie M. Villanueva, Ruben O. Donis, Nancy J. Cox
Publicado 2014

Genetic variation is the major determinant of individual differences in leukocyte endothelial adhesion.

por Michael A Grassi, Vidhya Rao, Kathryn P Winkler, Wei Zhang, Joseph D Bogaard, Siquan Chen, Bonnie LaCroix, Divya Lenkala, Jalees Rehman, Asrar B Malik, Nancy J Cox, R Stephanie Huang
Publicado 2014

Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

por Gengjie Jia, Yu Li, Hanxin Zhang, Ishanu Chattopadhyay, Anders Boeck Jensen, David R. Blair, Lea Davis, Peter N. Robinson, Torsten Dahlén, Søren Brunak, Mikael Benson, Gustaf Edgren, Nancy J. Cox, Xin Gao, Andrey Rzhetsky
Publicado 2019

High-throughput framework for genetic analyses of adverse drug reactions using electronic health records.

por Neil S Zheng, Cosby A Stone, Lan Jiang, Christian M Shaffer, V Eric Kerchberger, Cecilia P Chung, QiPing Feng, Nancy J Cox, C Michael Stein, Dan M Roden, Joshua C Denny, Elizabeth J Phillips, Wei-Qi Wei
Publicado 2021

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

por Alvaro N. Barbeira, Scott P. Dickinson, Rodrigo Bonazzola, Jiamao Zheng, Heather E. Wheeler, Jason M. Torres, Eric S. Torstenson, Kaanan P. Shah, Tzintzuni Garcia, Todd L. Edwards, Eli A. Stahl, Laura M. Huckins, GTEx Consortium, Dan L. Nicolae, Nancy J. Cox, Hae Kyung Im
Publicado 2018

A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

por Eric A. Hungate, Sapana R. Vora, Eric R. Gamazon, Takaya Moriyama, Timothy Best, Imge Hulur, Younghee Lee, Tiffany-Jane Evans, Eva Ellinghaus, Martin Stanulla, Jéremie Rudant, Laurent Orsi, Jacqueline Clavel, Elizabeth Milne, Rodney J. Scott, Ching-Hon Pui, Nancy J. Cox, Mignon L. Loh, Jun J. Yang, Andrew D. Skol, Kenan Onel
Publicado 2016

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.

por Federico Innocenti, Gregory M Cooper, Ian B Stanaway, Eric R Gamazon, Joshua D Smith, Snezana Mirkov, Jacqueline Ramirez, Wanqing Liu, Yvonne S Lin, Cliona Moloney, Shelly Force Aldred, Nathan D Trinklein, Erin Schuetz, Deborah A Nickerson, Ken E Thummel, Mark J Rieder, Allan E Rettie, Mark J Ratain, Nancy J Cox, Christopher D Brown
Publicado 2011