A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics

por Jessica Knox, Nicolas Joly, Edmond M. Linossi, José A. Carmona-Negrón, Natalia Jura, Lionel Pintard, William Zuercher, Peter J. Roy
Publicado 2021

Functional role of PGAM5 multimeric assemblies and their polymerization into filaments

por Karen Ruiz, Tarjani M. Thaker, Christopher Agnew, Lakshmi Miller-Vedam, Raphael Trenker, Clara Herrera, Maria Ingaramo, Daniel Toso, Adam Frost, Natalia Jura
Publicado 2019

Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization

por Christopher Agnew, Pelin Ayaz, Risa Kashima, Hanna S. Loving, Prajakta Ghatpande, Jennifer E. Kung, Eric S. Underbakke, Yibing Shan, David E. Shaw, Akiko Hata, Natalia Jura
Publicado 2021

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2

por Kushal Suryamohan, Devan Diwanji, Eric W. Stawiski, Ravi Gupta, Shane Miersch, Jiang Liu, Chao Chen, Ying-Ping Jiang, Frederic A. Fellouse, J. Fah Sathirapongsasuti, Patrick K. Albers, Tanneeru Deepak, Reza Saberianfar, Aakrosh Ratan, Gavin Washburn, Monika Mis, Devi Santhosh, Sneha Somasekar, G. H. Hiranjith, Derek Vargas, Sangeetha Mohan, Sameer Phalke, Boney Kuriakose, Aju Antony, Mart Ustav Jr, Stephan C. Schuster, Sachdev Sidhu, Jagath R. Junutula, Natalia Jura, Somasekar Seshagiri
Publicado 2021