Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces

por Myungjin Lee, Anita Changela, Jason Gorman, Reda Rawi, Tatsiana Bylund, Cara W. Chao, Bob C. Lin, Mark K. Louder, Adam S. Olia, Baoshan Zhang, Nicole A. Doria-Rose, Susan Zolla-Pazner, Lawrence Shapiro, Gwo-Yu Chuang, Peter D. Kwong
Publicado 2021

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

por James J. Steinhardt, Javier Guenaga, Hannah L. Turner, Krisha McKee, Mark K. Louder, Sijy O’Dell, Chi-I Chiang, Lin Lei, Andrey Galkin, Alexander K. Andrianov, Nicole A. Doria-Rose, Robert T. Bailer, Andrew B. Ward, John R. Mascola, Yuxing Li
Publicado 2018

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

por Erik L. Johnson, Nicole A. Doria-Rose, Jason Gorman, Jinal N. Bhiman, Chaim A. Schramm, Ashley Q. Vu, William H. Law, Baoshan Zhang, Valerie Bekker, Salim S. Abdool Karim, Gregory C. Ippolito, Lynn Morris, Penny L. Moore, Peter D. Kwong, John R. Mascola, George Georgiou
Publicado 2018

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

por Yen-Ting Lai, Tao Wang, Sijy O’Dell, Mark K. Louder, Arne Schön, Crystal S. F. Cheung, Gwo-Yu Chuang, Aliaksandr Druz, Bob Lin, Krisha McKee, Dongjun Peng, Yongping Yang, Baoshan Zhang, Alon Herschhorn, Joseph Sodroski, Robert T. Bailer, Nicole A. Doria-Rose, John R. Mascola, David R. Langley, Peter D. Kwong
Publicado 2019

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

por Christopher A. Cottrell, Kartik Manne, Rui Kong, Shuishu Wang, Tongqing Zhou, Gwo-Yu Chuang, Robert J. Edwards, Rory Henderson, Katarzyna Janowska, Megan Kopp, Bob C. Lin, Mark K. Louder, Adam S. Olia, Reda Rawi, Chen-Hsiang Shen, Justin D. Taft, Jonathan L. Torres, Nelson R. Wu, Baoshan Zhang, Nicole A. Doria-Rose, Myron S. Cohen, Barton F. Haynes, Lawrence Shapiro, Andrew B. Ward, Priyamvada Acharya, John R. Mascola, Peter D. Kwong
Publicado 2021