The molecular basis of JAK/STAT inhibition by SOCS1

par Nicholas P. D. Liau, Artem Laktyushin, Isabelle S. Lucet, James M. Murphy, Shenggen Yao, Eden Whitlock, Kimberley Callaghan, Nicos A. Nicola, Nadia J. Kershaw, Jeffrey J. Babon
Publié 2018

Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection.

par Lukasz Kedzierski, Edmond M Linossi, Tatiana B Kolesnik, E Bridie Day, Nicola L Bird, Benjamin T Kile, Gabrielle T Belz, Donald Metcalf, Nicos A Nicola, Katherine Kedzierska, Sandra E Nicholson
Publié 2014

Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.

par Ellen Menkhorst, Jian-Guo Zhang, Natalie A Sims, Phillip O Morgan, Priscilla Soo, Ingrid J Poulton, Donald Metcalf, Estella Alexandrou, Melissa Gresle, Lois A Salamonsen, Helmut Butzkueven, Nicos A Nicola, Evdokia Dimitriadis, Evdokia Dimitriadis
Publié 2011